Avoid positional markers

They usually just add noise. Let the functions and variable names along with the proper indentation and formatting give the visual structure to your code.

Most IDE support code folding feature that allows you to collapse/expand blocks of code (see Visual Studio Code folding regions).

Bad:

////////////////////////////////////////////////////////////////////////////////
// Client class
////////////////////////////////////////////////////////////////////////////////
class Client {
  id: number;
  name: string;
  address: Address;
  contact: Contact;

  ////////////////////////////////////////////////////////////////////////////////
  // public methods
  ////////////////////////////////////////////////////////////////////////////////
  public describe(): string {
    // ...
  }

  ////////////////////////////////////////////////////////////////////////////////
  // private methods
  ////////////////////////////////////////////////////////////////////////////////
  private describeAddress(): string {
    // ...
  }

  private describeContact(): string {
    // ...
  }
}

Good:

class Client {
  id: number;
  name: string;
  address: Address;
  contact: Contact;

  public describe(): string {
    // ...
  }

  private describeAddress(): string {
    // ...
  }

  private describeContact(): string {
    // ...
  }
}